The researchers checked the activity of 11£¬000 genes from the mouse livers£®and found that 46 changed with age in the normally fed mice£®The changes were associated with things like inflammation and free radical production£¨A´íÎó£©--probably bad news for mouse health£®£¨In the mice that had dieted all their lives£¬27 of those 46 genes continued to behave like young genes£®But the most surprising finding was that the mice that only started dieting in old age also benefited from 70 per cent of these gene changes£®£©
4.According to the author£¬which of the following most interested the researchers?
A) The mice that started dieting in old age£®
B)27 of those 46 old genes that continued to behave like young genes£®
C)Calorie restriction that works in people£®
D)Dieting that makes sure a drug is effective£®
4£® A¡£ ·ÖÎö£º½èÖúÌâ¸ÉÖгöÏÖµÄÐÞÊδÊmost interested ºÍºËÐÄ´Êresearchers×÷Ϊ´ð°¸ÏßË÷£¬Í¬Ê±×¢ÒⱻѡÏîÖгöÏֵĺËÐĽṹ£¬ÕâÑùÕÒµ½´ð°¸Ïà¹Ø¾ä£º
The researchers checked the activity of 11£¬000 genes from the mouse livers£®and found that 46 changed with age in the normally fed mice£® The changes were associated with things like inflammation and free radical production--probably bad news for mouse health£®In the mice that had dieted all their lives£¬27 of those 46 genes continued to behave like young genes£®But the most surprising finding£¨¸Ã½á¹¹ÓëÌâ¸ÉÖеÄmost interestedºôÓ¦£©was that the mice that only started dieting in old age also benefited from 70 per cent of these gene changes£®¸Ã¾ä°µÊ¾A±È¸üÄÜÈÃÑо¿Õ߸е½ÐËȤ£¬ÒòΪ¾ä×ÓÖÐÓÃÁËmost surprisingµÄ½á¹¹
¡°This is the first indication that these effects kick in pretty quickly,¡± says Huber Warner from the National Institute on Aging near Washington£¬D£®C£®£®
No one yet knows if calorie restriction works in people as it does in mice, but Spindler is hopeful£®£¨¸Ã¾ä·ñ¶¨ÁËC£©¡°There¡¯s attracting and tempting evidence out there that it will work£®¡±he says£®
If it does work in people£¬there might be good reasons for rejuvenating the liver£®As we get older, our bodies are less efficient at metabolizing drugs£¬for example£®A brief period of time of dieting£¬says Spindler, could be enough to make sure a drug is effective£®